Note that your messages are "Access Denied"; I would check permissions at the share and filesystem level.
In addition, if you're testing on different systems (e.g. running smbclient from a different system) both should have the same versions of Centrify software.
Not much more we can guide you through.
We've released 5.3.1 in May and I know of at least one issue being resolved by the upgrade from one of our community members.