Thank you for your response. Below are the answers to your questions:
1. What is the OS X version you are using?
OS X El Capitan 10.11.5
2. What kind and what version of smart card you are using?
Using my DoD CAC w/ a SCR3500 (Small USB foldable one)
3. What version of Centrify SmartCard Express you are using?
My SmartCard Assistant is Version 5.2.4.
4. Did you try other browsers like Chrome or Firefox?
Trying to access https://sofwebmail.socom.mil/OWA, neither Safari, Chrome,
or Firefox work, however, in Firefox, I can access DTS with my CAC.
- Pat