Hello Unisys! Welcome back to the Community Portal!
It appears you may be experiencing an issue with IWA. Are these users attempting to access the Admin/User/O365 portals from your internal network? If so, can you follow the below documentation links to test IWA and also confirm if the browsers are configured for silent authentication?
Verify IWA over HTTP - https://docs.centrify.com/en/centrify/adminref/index.html#page/cloudhelp/Scenario_IWA.09.html
How to configure browsers for silent authentication - https://docs.centrify.com/en/centrify/adminref/cloudhelp/cloud-admin-config-browser-silent-auth.html#
I would also recommend viewing the below KB article to troubleshoot your issue further:
KB-4257: Troubleshooting Integrated Windows Authentication (IWA) with Centrify Identity Service:
https://centrify.force.com/support/Centrify_KB_ArtDetail?Id=kA080000000GsTdCAK
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Re: Additional authentication request
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