Welcome back.
Ideally you'll use the latest and greatest client (5.3.4). It still provides support for OS X 10.10
I noticed that you're using Deployment Manager. Did you upgrade the manifest before trying to do this?
Here's a link to the OS X Sierra resource page:
https://www.centrify.com/support/macos-sierra-download
Check out the "Deployment Manager" box in the lower right.
Let us know if you have additional questions.
R.P